Kalanchoe sexangularis is an evergreen, robust, water-wise, succulent shrublet. It grows upright on square stems that are green when young and become brown and flaky as they mature. The stems have a tendency to be lax and droopy and lie flat as the leaves become too large and heavy for the thin stems to support. It does not exceed heights of 1.5 m and has an unlimited spread, as that is the nature of its growth habit. Its attractive, broad, glossy and deeply serrated foliage reach lengths of 50–120 mm. When grown in shade the leaves tend to be greenish red, more green than red, but when in full sun, they tend to be ruby red. The leaves also turn red when there is a drop in temperature during the winter months.